UVM Rescue is a state certified Advanced Life Support (ALS) ambulance. It is staffed and operated by University of Vermont students 24 hours a day, 365 days a year.

The primary responsibility of UVM Rescue is to provide emergency medical care to the University of Vermont, University of Vermont Helipad, and the University Health Center (UHC). UVM Rescue also provides primary back-up to Burlington, South Burlington, Shelburne, Winooski, Richmond, and other communities as part of its mutual aid plan.

UVM Rescue also works in conjunction with three local helicopters: North Country Life Flight, Life Net of New York, and the Darthmouth Hitchcock Air Response Team (DHART). UVM Rescue aids University Medical Center by transporting the patients who have been airlifted to the landing pad located behind UVM Rescue's quarters.

UVM Rescue responds to approximately 1,800 requests for an ambulance each year. These requests range in severity from ill students to life-threatening emergencies that include poisonings, multi-trauma, respiratory difficulties, and cardiac arrests.